Biopharmaceutical Automated Fill Machine Isolator

The Biomanufacturing Education & Skills Training (BEST) Center of Eastern North Carolina, operated by Wilson Community College, is expanding its current design to include simulated cleanrooms that will be utilized for training in drug product manufacturing. To provide a capstone experience for trainees, the expansion will feature an automated fill machine housed in an isolator that simulates a controlled environment. Wilson Community College is seeking proposals to build and install a unit that meets the user requirements listed within.

The design should facilitate advanced training on manual operations and aseptic techniques, with emphasis on educational value rather than high-throughput capability, operational flexibility, or additional premium features.

The contract will include multiple phases, including project kickoff and design review; equipment design, fabrication, assembly, integration, and programming; Factory Acceptance Testing (FAT); delivery and installation; startup and commissioning; functional and acceptance testing; training; delivery of required documentation; and final project acceptance. Interested vendors should provide a written proposal that describes their solution.

Proposal price shall constitute the total cost to the State for complete performance in accordance with the requirements and specifications herein, including equipment, materials, engineering and design, fabrication, system integration, software and controls, Factory Acceptance Testing (FAT), packaging, handling, freight and transportation, delivery, installation, startup and commissioning, acceptance testing, training, documentation, administrative costs, including travel, and other fees necessary to provide a complete and operational automated vial filling/isolator system.

The Vendor shall deliver Free-On-Board (FOB) Destination to the following location(s):

- BEST Center of Eastern NC, Wilson Community College, 4101 NC Highway 58 S, Wilson, NC 27893

Upon completion of the installation, the Vendor shall remove and properly dispose of all waste and debris from the installation site. The Vendor shall be responsible for leaving the installation area clean and ready to use.

**Submission method:** Vendor's proposals for this procurement must be submitted through the Sourcing Tool. **Electronic responses ONLY** will be accepted for this solicitation.

The term of the Contract shall begin on the date of final Contract execution (the "Effective Date") and shall continue until completion and acceptance of all requirements within the scope of work. Wilson Community College anticipates that the Project Scope of work will be completed within one (1) year of the Effective Date. The Vendor shall begin work under the Contract within ten (10) business days of the Effective Date.

Offer shall be valid for at least one hundred and twenty (120) days from date of bid opening.

**Evaluation criteria**, listed in descending order of importance:

1. Vendor Technical Approach (Section 5.5)
2. Vendor References (Section 4.8)
3. Vendor Experience (Section 4.7)
4. Financial Statements (Section 4.10)
5. Cost (Section 4.1 and Attachment: Pricing)

The warranty will apply from date equipment is put into operation for a minimum period of twelve (12) months or the length of the manufacturer's warranty, whichever is longer.